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Antibodies

Recombinant Drosha Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN301162L-50UL
100 ul
£346.00
AN301162L-100UL
About this Product
SKU:
AN301162L
Additional Names:
ETOHI;DROSHA;ETOHI2;HSA242976;RANSE3L;RN3;RNASE3L;RNASEN;Drosha double stranded RNA specific endoribonuclease;Drosha ribonuclease type III;Nuclear RNase III Drosha;p241;Protein Drosha;Putative protein p241 which interacts with transcription factor Sp1;Putative ribonuclease III;Ribonuclease 3;Ribonuclease III;Ribonuclease III nuclear;Ribonuclease type III nuclear;RibonucleaseIII;RN 3;RNase 3;RNase III;RNase3;RnaseIII;RNaseIII;RNC;Drosha
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B921
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
DROSHA(drosha ribonuclease III) Homo sapiens This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
Host:
Rabbit
Immunogen:
Recombinant Human Drosha protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies