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Antibodies

Recombinant LXRA Alpha Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN301127L-50UL
100 ul
£346.00
AN301127L-100UL
About this Product
SKU:
AN301127L
Additional Names:
RLD;NR1H;NR1H3;LXR-a;LXRA;RLD-1;LXR alpha;Group H;Member 3;NR1-H3;Nuclear Receptor Subfamily 1;LXRA Alpha
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B882
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant Human LXRA Alpha protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies