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Antibodies

Recombinant FBX32 Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN301124L-50UL
100 ul
£346.00
AN301124L-100UL
About this Product
SKU:
AN301124L
Additional Names:
FBX;FBXO;FBXO32;Fbx32;MAFbx;4833442G10Rik;AI430017;Atrogin 1;ATROGIN1;Atrogin-1;Atrophy gene 1;F box only protein 32;F-box only protein 32;F-box protein 32;fbxo25;FLJ32424;MGC108443;MGC137646;MGC33610;Muscle atrophy F box;Muscle atrophy F box protein;Muscle atrophy F-box protein;FBX32
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B879
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Host:
Rabbit
Immunogen:
Recombinant Human FBX32 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies