Recombinant Collagen IV Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN301106L-50UL
100 ul
£346.00
AN301106L-100UL
About this Product
- SKU:
- AN301106L
- Additional Names:
- COL4A,POREN,alpha 1 chain,Arresten,COL4A1 NC1 domain,Collagen alpha-1(IV) chain,Collagen IV alpha-1 polypeptide,Collagen of basement membrane,HANAC,ICH,POREN1,COL4A1,Type-IV Collagen
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B861
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Collagen IV protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_collagen_iv_monoclonal_antibody-an301106l
