Recombinant Glucocorticoid Receptor Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN301002L-50UL
100 ul
£346.00
AN301002L-100UL
About this Product
- SKU:
- AN301002L
- Additional Names:
- NR3C;nuclear receptor subfamily;glucocorticoid nuclear receptor variant;Nuclear receptor subfamily 3 group C member;GCCR;GCR;GCRST;GR;GRL;NR3C1;glucocorticoid nuclear receptor variant 1;Glucocorticoid receptor;Grl1;group C;member 1 (glucocorticoid receptor);nuclear receptor subfamily 3;Nuclear receptor subfamily 3 group C member 1
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B753
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Glucocorticoid Receptor protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_glucocorticoid_receptor_monoclonal_antibody-an301002l
