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Antibodies

Recombinant RPA32/RPA2 Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN300951L-50UL
100 ul
£346.00
AN300951L-100UL
About this Product
SKU:
AN300951L
Additional Names:
REPA;RPA;REPA2;RP-A p32;RP-A p34;RPA32;RPA2;RP-Ap32;RP-Ap34;RPA34;32kDa;60S acidic ribosomal protein P1;AA409079;AI325195;AU020965;ik:tdsubc_2g1;M(2)21C;MGC137236;OTTHUMP00000004008;p32;p34;RCJMB04_6d17 replication protein A2;Replication factor A protein 2;Replication protein A;Replication protein A 32 kDa subunit;Replication protein A 32kDa subunit;Replication protein A 34 kDa subunit;Replication protein A2;Replication Protein A2 (32kDa);RFA;RF-A protein 2;RFA2;Rf-A2;RP21C;RPA 2;RPA 32;RpLP1;RpP2;xx:tdsubc_2g1;zgc:109822;RFA2
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B702
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.
Host:
Rabbit
Immunogen:
Recombinant Human RPA32/RPA2 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies