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Antibodies

Recombinant Bag3 Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN300926L-50UL
100 ul
£346.00
AN300926L-100UL
About this Product
SKU:
AN300926L
Additional Names:
MFM;CAIR;Bcl-2-associated athanogene;BAG family molecular chaperone regulator;BAG;BAG3;BAG-3;BIS;CAIR-1;MFM6;BAG family molecular chaperone regulator 3;Bcl-2-associated athanogene 3;Bcl-2-binding protein Bis;Bcl-2-associated athanogene 3;Bcl-2-binding protein Bis;BIS;BAG 3;BAG family molecular chaperone regulator 3;Bcl 2 binding protein;BCL2 associated athanogene 3;BCL2 binding athanogene 3;CAIR 1;Docking protein CAIR 1;Docking protein CAIR-1;Bag-3
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B873
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Host:
Rabbit
Immunogen:
Recombinant Human Bag3 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies