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Antibodies

Recombinant MDR1 Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN300819L-50UL
100 ul
£346.00
AN300819L-100UL
About this Product
SKU:
AN300819L
Additional Names:
MDR;PGY;ABC;ABCB;P-glycoprotein;Phospholipid transporter ABCB;ATP-dependent translocase ABCB;ATP-binding cassette sub-family B member;ABC20;CD243;CLCS;GP170;MDR1;P-GP;PGY1;P Glycoprotein;ABCB1;ATP-binding cassette sub-family B member 1;ATP-dependent translocase ABCB1;P-glycoprotein 1;Phospholipid transporter ABCB1;MDR-1;P-gp;gp170;ABC-B1;ATP binding cassette;Colchicin sensitivity;Doxorubicin resistance;member 1;Multidrug resistance 1;Multidrug resistance protein 1;P glycoprotein 1;P gp;sub family B (MDR/TAP)
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B762
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Host:
Rabbit
Immunogen:
Recombinant Human MDR1 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies