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Antibodies

Recombinant MDR1 Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN300819L-50UL
100 ul
£346.00
AN300819L-100UL
About this Product
SKU:
AN300819L
Additional Names:
MDR,PGY,ABC,ABCB,P-glycoprotein,Phospholipid transporter ABCB,ATP-dependent translocase ABCB,ATP-binding cassette sub-family B member,ABC20,CD243,CLCS,GP170,MDR1,P-GP,PGY1,P Glycoprotein,ABCB1,ATP-binding cassette sub-family B member 1,ATP-dependent translocase ABCB1,P-glycoprotein 1,Phospholipid transporter ABCB1,MDR-1,P-gp,gp170,ABC-B1,ATP binding cassette,Colchicin sensitivity,Doxorubicin resistance,member 1,Multidrug resistance 1,Multidrug resistance protein 1,P glycoprotein 1,P gp,sub family B (MDR/TAP)
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B762
Clonality:
Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Host:
Rabbit
Immunogen:
Recombinant Human MDR1 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies