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Antibodies

Recombinant PUMA Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN300815L-50UL
100 ul
£346.00
AN300815L-100UL
About this Product
SKU:
AN300815L
Additional Names:
BBC;PUMA;BBC3;BBC 3;BBC3_HUMAN;BCL 2 binding component 3;BCL2 binding component 3;Bcl-2-binding component 3;JFY 1;JFY1;JFY-1;p53 up regulated modulator of apoptosis;p53 Upregulated Modulator of Apoptosis;p53 up-regulated modulator of apoptosis;PUMA alpha;PUMA/JFY1
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B758
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant Human PUMA protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies