Recombinant ASK1 Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN300808L-50UL
100 ul
£346.00
AN300808L-100UL
About this Product
- SKU:
- AN300808L
- Additional Names:
- ASK;MEKK;MAP3K;MAPKKK;MAP3K5;ASK1;MAPKKK5;MEKK5;Apoptosis signal regulating kinase 1;Apoptosis signal-regulating kinase 1;ASK 1;ASK-1;M3K5;MAP/ERK kinase kinase 5;MAPK/ERK kinase kinase 5;MEK kinase 5;MEKK 5;Mitogen activated protein kinase kinase kinase 5;mitogen-activated protein kinase kinase kinase 5
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B751
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ASK1 protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_ask1_monoclonal_antibody-an300808l
