Recombinant ERG Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN300724L-50UL
100 ul
£346.00
AN300724L-100UL
About this Product
- SKU:
- AN300724L
- Additional Names:
- ERG;Avian erythroblastosis virus E-26 (v-ets) oncogene related;D030036I24Rik;Erg 3;ERG/EWS fusion gene;ERG/FUS fusion gene;ERG/TMPSSR2 fusion gene;ERG1;ERG2;ets related;ETS-related gene;included;isoform CRA_e;KCNH2;Oncogene ERG;p55;TMPRSS2/ERG fusion;Transcriptional regulator ERG;transcriptional regulator ERG (transforming protein ERG);Transforming protein ERG;v ets avian erythroblastosis virus E26 oncogene;v ets avian erythroblastosis virus E26 oncogene related;v ets erythroblastosis virus E26 oncogene homolog;v ets erythroblastosis virus E26 oncogene like;v ets erythroblastosis virus E26 oncogene like isoform 2;v-ets erythroblastosis virus E26 oncogene;v-ets erythroblastosis virus E26 oncogene homolog (avian);V-ets erythroblastosis virus E26 oncogene like (Avian)
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B663
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ERG protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_erg_monoclonal_antibody-an300724l
