Recombinant MLKL Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN300716L-50UL
100 ul
£346.00
AN300716L-100UL
About this Product
- SKU:
- AN300716L
- Additional Names:
- hMLKL;MLKL;9130019I15Rik;FLJ34389;Mixed lineage kinase domain like;Mixed lineage kinase domain like protein;Mixed lineage kinase domain like pseudokinase;Mixed lineage kinase domain-like protein
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B655
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human MLKL protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Avian, Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_mlkl_monoclonal_antibody-an300716l
