Recombinant MDM2 Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN300707L-50UL
100 ul
£346.00
AN300707L-100UL
About this Product
- SKU:
- AN300707L
- Additional Names:
- hdm;MDM;MDM2;ACTFS;HDMX;hdm2;Double minute 2 protein;E3 ubiquitin-protein ligase Mdm2;Hdm 2;MDM 2;MDM2 oncogene E3 ubiquitin protein ligase;Mdm2 p53 E3 ubiquitin protein ligase homolog;Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa;MDM2BP;Mouse Double Minute 2;MTBP;Murine Double Minute Chromosome 2;Oncoprotein Mdm2;p53 Binding Protein Mdm2;p53-binding protein Mdm2;Ubiquitin protein ligase E3 Mdm2
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B646
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human MDM2 protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_mdm2_monoclonal_antibody-an300707l
