Recombinant XIAP Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN300702L-50UL
100 ul
£346.00
AN300702L-100UL
About this Product
- SKU:
- AN300702L
- Additional Names:
- ILP;XLP;API;BIRC;Inhibitor of apoptosis protein;Baculoviral IAP repeat-containing protein;IAP;XIAP;API3;BIRC4;IAP-3;ILP1;MIHA;XLP2;hIAP-3;hIAP3;X-linked inhibitor of apoptosis;Baculoviral IAP repeat-containing protein 4;E3 ubiquitin-protein ligase XIAP;IAP-like protein;Inhibitor of apoptosis protein 3;RING-type E3 ubiquitin transferase XIAP;X-linked inhibitor of apoptosis protein;IAP3
- Application:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B641
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human XIAP protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_xiap_monoclonal_antibody-an300702l
