Recombinant Phospho-STAT5 (Tyr694) Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN300691L-50UL
100 ul
£346.00
AN300691L-100UL
About this Product
- SKU:
- AN300691L
- Additional Names:
- MGF;STAT5;STAT5A;STA5A;Mammary gland factor;Signal transducer and activator of transcription 5A;STAT 5;STAT 5A;STAT5A/B
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B630
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to residues around (Tyr694) of Human Phospho-STAT5
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_phospho_stat5_(tyr694)_monoclonal_antibody-an300691l
