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Antibodies

Recombinant ZAP-70 Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN300642L-50UL
100 ul
£346.00
AN300642L-100UL
About this Product
SKU:
AN300642L
Additional Names:
IMD;ADMIO;ZAP;ZAP70;ADMIO2;IMD48;SRK;STCD;STD;TZK;ZAP-70;70 kDa zeta associated protein;70 kDa zeta-associated protein;EC 2.7.10.2;FLJ17670;FLJ17679;Selective T cell defect;Syk related tyrosine kinase;Syk-related tyrosine kinase;Truncated ZAP kinase;Tyrosine protein kinase ZAP70;Tyrosine-protein kinase ZAP-70;ZAP 70;Zeta chain associated protein kinase 70kD;Zeta chain associated protein kinase 70kDa;Zeta chain associated protein kinase 70kDa isoform 1;Zeta chain associated protein kinase 70kDa isoform 2;Zeta chain of T cell receptor associated protein kinase 70;Zeta chain TCR associated protein kinase 70kD;Zeta chain TCR associated protein kinase 70kDa;SRK;STD;TZK;ZAP70
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B577
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant Human ZAP-70 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies