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Antibodies

Recombinant Phospho-STAT3 (Tyr705) Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN300638L-50UL
100 ul
£346.00
AN300638L-100UL
About this Product
SKU:
AN300638L
Additional Names:
STAT;Signal Transducer and Activator of Transcription;ADMIO;ADMIO1;APRF;HIES;STAT3;Acute-Phase Response Factor;Signal Transducer and Activator of Transcription 3;1110034C02Rik;Acute Phase Response Factor;AW109958;DNA binding protein APRF;FLJ20882;MGC16063;Signal transducer and activator of transcription 3 (acute phase response factor);STAT 3
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B573
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to residues around (Tyr705) of Human Phospho-STAT3
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Porcine, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies