Recombinant CD166/ALCAM Monoclonal Antibody
Product Sizes
100 ul
£402.00
AN300586P-100UL
About this Product
- SKU:
- AN300586P
- Additional Names:
- UCHL;Uchl1;HEL-117;HEL-S-53;NDGOA;PARK5;PGP 9.5;PGP9.5;PGP95;SPG79;Ubiquitin C-terminal hydrolase L1;Uch-L1
- Application:
- Immunoprecipitation, Western Blot
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- B521
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target.
- Host:
- Rabbit
- Immunogen:
- Recombinant Rat CD166/ALCAM protein
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:alcam_monoclonal_antibody-an300586p
