Recombinant HE4/WFDC2/WAP5 Monoclonal Antibody
Product Sizes
100 ul
£402.00
AN300583P-100UL
About this Product
- SKU:
- AN300583P
- Application:
- IHC-Paraffin
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- B518
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2/HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2/HE4 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
- Host:
- Rabbit
- Immunogen:
- Recombinant Rat HE4/WFDC2/WAP5
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:wap5_monoclonal_antibody-an300583p
