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Antibodies

Recombinant TNF-alpha Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300581P-100UL
About this Product
SKU:
AN300581P
Additional Names:
MGC,Tnfsf,TNF-a,Cachectin,DIF,ICD1,ICD2,Membrane Form,MGC124630,N-terminal fragment,NTF,RATTNF,Soluble Form,TNF-alpha,Tumor Necrosis Factor,Tumor Necrosis Factor Ligand Superfamily Member 2,Tnf,Tnfa,Tnfsf2
Application:
Immunocytochemistry, Immunofluorescence
Buffer:
PBS
translate.label.attr.clone:
B516
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
TNF-A Alpha is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-A Alpha. Monomeric mouse TNF-A Alpha is 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD protein. TNF-A Alpha forms multimeric complexes, stable trimers are most common in solution. A 26 kD membrane form of TNF-A Alpha has also been described. TNF-A Alpha binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.
Host:
Rabbit
Immunogen:
Recombinant Rat TNF-alpha Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody