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Antibodies

Recombinant IL36B/IL1F8 Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300570P-100UL
About this Product
SKU:
AN300570P
Additional Names:
Il1f;Interleukin-1 family member;IL-1F;IL-1F8;Interleukin-1 family member 8;Interleukin-36 beta;Fil1e;Il1f8;Il36b
Application:
Western Blot
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
B505
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines includes four members, with three having pro-inflammatory effects such as IL1F8 and the fourth member being an IL-1 receptor antagonist (IL-1Ra). IL-1 family members exert their effects through binding to receptors that belong to the IL-1 receptor (IL-1R) family. IL1F8 exerts proinflammatory effects in primary human joint cells. Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in some human serum samples tested, including samples from patients with rheumatoid arthritis. IL1F8 also activated NK-K KappaB.
Host:
Rabbit
Immunogen:
Recombinant Mouse IL36B/IL1F8 Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody