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Antibodies

Recombinant CD19 Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN300527P-100UL
About this Product
SKU:
AN300527P
Additional Names:
B-lymphocyte antigen CD;Differentiation antigen CD;B-lymphocyte antigen CD19;Differentiation antigen CD19;Cd19;B4;AW495831;CD19 molecule;CVID3
Application:
IHC-Paraffin
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
B457
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.
Host:
Rabbit
Immunogen:
Recombinant Mouse CD19 Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody