Recombinant Ly108/SLAMF6 Monoclonal Antibody
Product Sizes
100 ul
£402.00
AN300500P-100UL
About this Product
- SKU:
- AN300500P
- Additional Names:
- SLAMF;Ly108;Slamf6;NTB-A;KAL1;Ly108
- Application:
- Western Blot
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- B430
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6/Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6/Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6/Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6/Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6/Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse Ly108/SLAMF6 Protein
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:slamf6_monoclonal_antibody-an300500p
