Recombinant CD27 Monoclonal Antibody
Product Sizes
100 ul
£402.00
AN300476P-100UL
About this Product
- SKU:
- AN300476P
- Additional Names:
- Tnfrsf;Tnfrsf7;Cd27;T14;S152;TNFRSF7;CD27 antigen;CD27L receptor;S152;T-cell activation antigen CD27;Tp55;Tumor necrosis factor receptor superfamily member 7
- Application:
- Flow Cytometry, Immunocytochemistry, Immunofluorescence
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- B406
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse CD27 protein
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-recombinant_cd27_monoclonal_antibody-an300476p
