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Antibodies

Recombinant CD95/APO-1/TNFRSF6/FAS Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300460P-100UL
About this Product
SKU:
AN300460P
Additional Names:
Apt,APO,Tumor necrosis factor receptor superfamily member,Tnfrsf,ALPS1A,APO1,Apo-1 antigen,Apoptosis-mediating surface antigen FAS,CD95,FAS1,FASLG receptor,FASR,FASTM,Tumor necrosis factor receptor superfamily member 6,Apt1,Tnfrsf6,Fas,AI196731 Protein,APO1 Protein,APT1 Protein,CD95 Protein,lpr Protein,TNFR6 Protein,Tnfrsf6 Protein
Application:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Buffer:
PBS
translate.label.attr.clone:
B386
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Host:
Rabbit
Immunogen:
Recombinant Mouse CD95/APO-1/TNFRSF6/FAS Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Immunofluorescence analysis of mouse FAS in Mouse splenocytes. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse FAS monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 594-conjugated Goat Anti-rabbit IgG secondary antibody (red).
Flow cytometric analysis of Mouse FAS(CD95) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse FAS(CD95), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.