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Antibodies

Recombinant PDHA1 Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN300453P-100UL
About this Product
SKU:
AN300453P
Additional Names:
PDHA1;PDHA;PDHAD;PDHCE1A;PHE1A;E1 alpha polypeptide 1;mitochondrial;ODPA;PDH;PDHE1 A type I;PDHE1-A type I;PDHA Alpha;Pyruvate Dehydrogenase (lipoamide) alpha 1;Pyruvate dehydrogenase complex;Pyruvate Dehydrogenase E1 alpha;Pyruvate dehydrogenase E1 component subunit alpha;somatic form
Application:
Immunocytochemistry, Immunofluorescence
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
B379
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant Human PDHA1 Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody