Recombinant PSGL-1/CD162/SELPLG Monoclonal Antibody
Product Sizes
100 ul
£402.00
AN300442P-100UL
About this Product
- SKU:
- AN300442P
- Additional Names:
- P selectin glycoprotein ligand;P-selectin glycoprotein ligand;CD 162;CD162;CD162 antigen;CLA;Cutaneous lymphocyte associated associated antigen;P selectin glycoprotein ligand 1;P selectin glycoprotein ligand 1 precursor;P-selectin glycoprotein ligand 1;PSGL 1;PSGL1;PSGL-1;Selectin P ligand;SELPL;SELPLG;PEN-5
- Application:
- Flow Cytometry, IHC-Paraffin
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- B368
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human PSGL-1/CD162/SELPLG Protein
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:selplg_monoclonal_antibody-an300442p
