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Antibodies

Recombinant RRM2B/P53R2 Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300433P-100UL
About this Product
SKU:
AN300433P
Additional Names:
P53R;RRM2B;MTDPS8A;MTDPS8B;P53R2
Application:
IHC-Paraffin, Immunocytochemistry, Immunofluorescence
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
B359
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Host:
Rabbit
Immunogen:
Recombinant Human RRM2B/P53R2 protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Immunohistochemistry of paraffin-embedded human tonsil using RRM2B/P53R2 Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded human squamous cancer using RRM2B/P53R2 Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded human skeletal muscle using RRM2B/P53R2 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of RRM2B in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Y RRM2B monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm and Nucleus.