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Antibodies

Recombinant Phospho-MEK1/2 (Ser217, 2210) Monoclonal Antibody

Product Sizes
20 ul
£167.00
AN300366L-20UL
100 ul
£402.00
AN300366L-100UL
About this Product
SKU:
AN300366L
Additional Names:
MEK;MKK;CFC;MAPKK;PRKMK;MAP2K;CFC3;MAPKK1;MEK1;MKK1;PRKMK1;MAP2K1;Dual specificity mitogen activated protein kinase kinase 1;Dual specificity mitogen-activated protein kinase kinase 1;ERK activator kinase 1;kinase 1;MAP kinase kinase 1;MAP kinase/Erk kinase 1;MAPK/ERK kinase 1;MAPKK 1;MEK 1;MEKK1;Mitogen activated protein kinase kinase 1;MKK 1;MP2K1;Protein kinase mitogen activated;Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1)
Application:
Western Blot
Buffer:
10 mM sodium HEPES, 150 mM NaCl, 100 ug/mL protein protectant, 50% glycerol, pH 7.5
translate.label.attr.clone:
B288
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Host:
Rabbit
Immunogen:
A synthetic phosphopeptide corresponding to residues around Ser218 and Ser222 of the Human MEK1
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Western blot analysis of extracts from serum-starved Raji, untreated (line A); treated with TPA (200 nM, 30 min) (line B); treated with TPA and L Lambda-phosphatase (line C) using Phospho-MEK1/2 (Ser217, 221) Antibody, Rabbit MAb at 1:1000 dilution.
Western blot analysis of extracts from serum-starved Raji, untreated (-) or treated with TPA (200 nM, 30 min) (+), using Phospho-MEK1/2 (Ser217, 221) Antibody, Rabbit Mab at 1:1000 dilution. (upper) or Anti-MEK1 Antibody, Rabbit Polyclonal (middle) at 1:500 dilution. or Beta-Tubulin Loading Control Antibody, Mouse Mab at 1:20000 dilution.
Western blot analysis of extracts from serum-starved Raji, untreated (line A); treated with TPA (200 nM, 30 min), without peptide (line B) or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-MEK1/2 (Ser217, 221) Antibody, Rabbit MAb at 1:1000 dilution.
Western blot analysis of extracts from serum-starved Raji, treated with TPA (200 nM, 30 min), using Phospho-MEK1/2 (Ser217, 221) Antibody, Rabbit Mab (Sino Biological) and other brands' antibodies (Company C) at dilution. of 1:2000, 1:10000.