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Antibodies

Recombinant ASGR2/ASGPR2 Monoclonal Antibody

Product Sizes
20 ul
£189.00
AN300272P-20UL
100 ul
£402.00
AN300272P-100UL
About this Product
SKU:
AN300272P
Additional Names:
ASGR;ASGPR;ASGP-R;CLEC4H;ASGR2;ASGP-R2;ASGPR2;CLEC4H2;HBXBP;HL-2
Application:
Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Immunofluorescence
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
B190
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Host:
Rabbit
Immunogen:
Recombinant Human ASGR2 / ASGPR2 protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Flow cytometric analysis of Human ASGR2 expression on HepG2 cells. Cells were stained with purified anti-Human ASGR2, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Immunofluorescence analysis of ASGR2 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-human ASGR2 Monoclonal Antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI for nuclear staining (blue).
Immunohistochemistry of paraffin-embedded human liver using ASGR2 / ASGPR2 Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded human cirrhosis using ASGR2 / ASGPR2 Monoclonal Antibody at dilution of 1:200.