Recombinant CD46 Monoclonal Antibody
Product Sizes
100 ul
£402.00
AN300250P-100UL
About this Product
- SKU:
- AN300250P
- Additional Names:
- MIC;AHUS;TRA2.;AHUS2;MCP;MIC10;TLX;TRA2.10;CD46;CD46 molecule;Membrane Cofactor Protein;Trophoblast Leukocyte Common Antigen
- Application:
- IHC-Paraffin, Immunocytochemistry, Immunofluorescence
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- B168
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CD46 protein
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-recombinant_cd46_monoclonal_antibody-an300250p
