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Antibodies

Recombinant GSTM2 Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300247P-100UL
About this Product
SKU:
AN300247P
Additional Names:
GST;GSTM2;GST4;GSTM;GSTM2-2;GTHMUS;Glutathione S alkyltransferase M2;Glutathione S aralkyltransferase M2;Glutathione S aryltransferase M2;Glutathione S transferase 4;Glutathione S transferase M1;Glutathione S transferase M2 (muscle);Glutathione S transferase Mu 2;Glutathione S transferase Mu 2 (muscle);glutathione S-transferase mu 2;glutathione S-transferase mu 2 (muscle);GST class mu 2;GST class-mu 2;GST muscle;MGC117303;S (hydroxyalkyl)glutathione lyase M2
Application:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
B165
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
Host:
Rabbit
Immunogen:
Recombinant Human GSTM2 protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Immunofluorescence analysis of GSTM2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-human GSTM2 Monoclonal Antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI for nuclear staining (blue).Positive staining was localized to Cytoplasm.
Immunoprecipitation analysis using 2 uL anti-GSTM2 Monoclonal Antibody and 60 ug of Immunomagnetic beads Protein G. Western blot was performed from the immunoprecipitate using GSTM2 Monoclonal Antibody at a dilution of 1:100. Lane A:0.5 mg Hela Whole Cell Lysate, Lane B:0.5 mg Jurkat Whole Cell Lysate
Western Blot with GSTM2 Monoclonal Antibody at dilution of 1:500. Lane A: 293T Whole Cell Lysate, Lane B: 293 Whole Cell Lysate, Lysates/proteins at 30 ug per lane.