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Antibodies

Recombinant CALML5 Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300241P-100UL
About this Product
SKU:
AN300241P
Additional Names:
Calmodulin like;Calmodulin-like protein;CALML;CALL5_HUMAN;Calmodulin like 5;Calmodulin-like protein 5;Calmodulin-like skin protein;CLSP;CALML5
Application:
IHC-Paraffin
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
B159
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5/CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5/CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5/CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5/CLSP have been characterized by NMR spectroscopy. The mobility of CALML5/CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.
Host:
Rabbit
Immunogen:
Recombinant Human CALML5 protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody