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Antibodies

Recombinant SAA4 Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300231P-100UL
About this Product
SKU:
AN300231P
Additional Names:
Amyloid A;C SAA;Constitutively expressed serum amyloid A protein;C-SAA;SAA 4;SAA4 protein;SAA4_HUMAN;serum;Serum amyloid A 4 protein;Serum amyloid A4 constitutive;Serum amyloid A-4 protein;CSAA;SAA4;serum;Constitutively expressed serum amyloid A protein (C-SAA)
Application:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
B149
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
SAA4 is a member of the SAA family. SAA proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1, SAA2, and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma, infection, inflammation, and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL, but this group of SAA constitutes more than 90% of all the SAA during homeostasis, and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice. It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown, and its serum concentration has no association with those of other major apolipoproteins.
Host:
Rabbit
Immunogen:
Recombinant Human SAA4 protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Flow cytometric analysis of Human SAA4 expression on HepG2 cells. The cells were stained with purified anti-Human SAA4, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Immunofluorescence analysis of Human SAA4 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human SAA4 Monoclonal Antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI for nuclear staining (blue). Positive staining was localized to cytoplasm.
Western Blot with SAA4 Monoclonal Antibody at dilution of 1:500. Lane A: 293T Whole Cell Lysate, Lysates/proteins at 30 ug per lane.