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Antibodies

Recombinant CCR1 Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300172P-100UL
About this Product
SKU:
AN300172P
Additional Names:
CCR;CMKR;CMKBR;SCYAR;CKR;CD191;CKR-1;CKR1;CMKBR1;HM145;MIP1aR;SCYAR1;CCR1;CMKR1;C-C chemokine receptor type 1;C-C CKR-1;CC-CKR-1;CCR-1;CD_antigen: CD191;cluster of differentiation 191;LD78 receptor;Macrophage inflammatory protein 1-alpha receptor;MIP-1alpha-R;RANTES-R
Application:
IHC-Paraffin
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
A1286
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2005]
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to the center region of the Human CCR1
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody