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Antibodies

Recombinant Phospho-PLCG Gamma1 (Tyr783) Monoclonal Antibody

Product Sizes
20 ul
£189.00
AN300148L-20UL
100 ul
£402.00
AN300148L-100UL
About this Product
SKU:
AN300148L
Additional Names:
PLCG;phospholipase C gamma;NCKAP;PLCgamma;PLC;PLCG1;NCKAP3;PLC-II;PLC1;PLC148;PLCgamma1;phospholipase C gamma 1;NCKAP3;phospholipase C gamma 1;PLC1;PLC148;PLCgamma1;PLC-II
Application:
Western Blot
Buffer:
10 mM sodium HEPES, 150 mM NaCl, 100 ug/mL protein protectant, 50% glycerol, pH 7.5
translate.label.attr.clone:
A1262
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 2 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
A synthetic phosphopeptide corresponding to residues around Tyr783 of the Human PLCG Gamma1
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Western blot analysis of extracts from serum-starved A-431, untreated (-) or treated with EGF (Cat: PKSH031641) (50 ng/mL, 10min; +) , using Phospho-PLCG Gamma1 (Tyr783) Monoclonal Antibody at 1:1000 dilution (upper) or Beta-Tubulin Loading Control Antibody, Mouse MAb at 1:20000 dilution (lower).
Western blot analysis of extracts from serum-starved A-431, treated with EGF (Cat: PKSH031641) (50 ng/mL, 10min), using Phospho-PLCG Gamma1 (Tyr783) Monoclonal Antibody and other brands' antibodies (Company C) at dilution of 1:1000, 1:10000.
Western blot analysis of extracts from serum-starved A431, untreated (line A); treated with EGF (Cat: PKSH031641)(50 ng/mL, 10min)(line B); treated with EGF and L Lambda-phosphatase (line C) using Phospho-PLCG Gamma1 (Tyr783) Monoclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts from serum-starved A431, untreated (line A); treated with EGF (Cat: PKSH031641)(50 ng/mL, 10min), without peptide (line B) or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-PLCG Gamma1 (Tyr783) Monoclonal Antibody at 1:1000 dilution.