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Antibodies

Recombinant p63(alpha) Monoclonal Antibody

Product Sizes
20 ul
£189.00
AN300136P-20UL
100 ul
£402.00
AN300136P-100UL
About this Product
SKU:
AN300136P
Additional Names:
OFC,EEC,SHFM,AIS,B(p51A),B(p51B),EEC3,KET,LMS,NBP,OFC8,RHS,SHFM4,TP53CP,TP53L,TP73L,p40,p51,p53CP,p63,p73H,p73L,TP63,Amplified in squamous cell carcinoma,Chronic ulcerative stomatitis protein,CUSP,DN p63 alpha 1,DNp63,id:ibd3516,Keratinocyte transcription factor,Keratinocyte transcription factor KET,MGC115972,MGC192897,OTTHUMP00000209732,OTTHUMP00000209733,OTTHUMP00000209734,OTTHUMP00000209735,OTTHUMP00000209737,OTTHUMP00000209738,OTTHUMP00000209739,OTTHUMP00000209740,OTTHUMP00000209741,OTTHUMP00000209742,OTTHUMP00000209743,OTTHUMP00000209744,P51/P63,p53-related protein p63,TAp63alpha,Transformation related protein 63,Transformation-related protein 63,Trp53rp1,Trp63,Tumor protein 63,Tumor protein p53-competing protein,Tumor protein p53-like,tumor protein p63,Tumor protein p63 deltaN isoform delta,Tumor protein p73,Tumor protein p73-like,AIS,B(p51A),B(p51B),EEC3,KET,LMS,NBP,OFC8,p40,p51,p53CP,p63,p73H,p73L,RHS,SHFM4,TP53CP,TP53L,TP63,TP73L
Application:
IHC-Paraffin
Buffer:
PBS
translate.label.attr.clone:
A1250
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 5.
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to the C-terminus of the human p63(alpha p63).
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies