Recombinant S100A1 Monoclonal Antibody
Product Sizes
100 ul
£402.00
AN300114P-100UL
About this Product
- SKU:
- AN300114P
- Additional Names:
- S100a;AI266795;S100;S100a1;Protein S100-A1;S-100 protein alpha chain;S-100 protein subunit alpha;S100A;S100-alpha
- Application:
- IHC-Paraffin
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- A1228
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- S100A1 is a Ca2+ binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse S100A1 protein
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-recombinant_s100a1_monoclonal_antibody-an300114p
