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Antibodies

Recombinant Phospho-Stat6 (Tyr641) Monoclonal Antibody

Product Sizes
20 ul
£189.00
AN300083L-20UL
100 ul
£402.00
AN300083L-100UL
About this Product
SKU:
AN300083L
Additional Names:
D12S;STAT;Signal Transducer and Activator of Transcription;D12S1644;IL-4-STAT;STAT6B;STAT6C;STAT6;IL-4 Stat;Signal Transducer and Activator of Transcription 6;12S1644;IL 4 STAT;IL4 STAT;Interleukin 4 Induced;Interleukin 4 Induced Transcription Factor IL4 STAT;interleukin4 induced;Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced;Signal Transducer And Activator Of Transcription 6 Nirs Variant 1;STAT 6;STAT interleukin4 induced;Transcription factor IL 4 STAT
Application:
Western Blot
Buffer:
10 mM sodium HEPES, 150 mM NaCl, 100 ug/mL protein protectant, 50% glycerol, pH 7.5
translate.label.attr.clone:
A1193
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
A synthetic phosphopeptide corresponding to residues around Tyr641 of the Human Stat6
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with IL4 (100 ng/mL, 15min; +), using Phospho-Stat6 (Tyr641) Monoclonal Antibody at 1:10000 dilution (upper) or Anti-STAT6 Antibody, Rabbit PAb at 1:1000 dilution (lower).
Western blot analysis of extracts from serum-starved Hela, treated with IL4(100 ng/mL, 15 min), using Phospho-Stat6 (Tyr641) Monoclonal Antibody and other brands' antibodies (Company C) at dilution of 1:1000, 1:10000 and 1:200000.
Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with IL4(100 ng/mL, 15min)(line B); treated with IL4 and L Lambda-phosphatase (line C) using Phospho-Stat6 (Tyr641) Monoclonal Antibody at 1:10000 dilution.
Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with IL4(100 ng/mL, 15min), without peptide (line B) or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-Stat6 (Tyr641) Monoclonal Antibody at 1:10000 dilution.