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Antibodies

Recombinant BACE1 Monoclonal Antibody

Product Sizes
100 ul
£402.00
AN300071P-100UL
About this Product
SKU:
AN300071P
Additional Names:
ASP;HSPC;KIAA;Beta-secretase;Aspartyl protease;Beta-site APP cleaving enzyme;Membrane-associated aspartic protease;Beta-site amyloid precursor protein cleaving enzyme;Memapsin;BACE1;ASP2;BACE;HSPC104;KIAA1149;Memapsin-2;Beta-secretase 1;Aspartyl protease 2;Beta-site amyloid precursor protein cleaving enzyme 1;Beta-site APP cleaving enzyme 1;Membrane-associated aspartic protease 2;Beta Secretase 1;Memapsin 2
Application:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
A1181
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
BACE-1 (beta-site APP cleaving enzyme-1) is an aspartic protease and an integral membrane protein . It is the major beta secretase, and together with the gamma secretase, is responsible for generating the amyloid beta peptide (A beta ) from the amyloid precursor protein (APP)
Host:
Rabbit
Immunogen:
Recombinant Human BACE1 protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Flow cytometric analysis of Human BACE1 expression on Jurkat cells. The cells were stained with purified anti-Human BACE1, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Immunofluorescence analysis of Human BACE1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human AK4 Monoclonal Antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI for nuclear staining (blue). Positive staining was localized to cytoplasm.