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Antibodies

Recombinant Insulin Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN300052P-100UL
About this Product
SKU:
AN300052P
Additional Names:
MODY;IDDM;IDDM1;IDDM2;ILPR;IRDN;MODY10;INS;Insulin;Connecting Peptide;Insulin A chain;Insulin B chain;Preproinsulin;Proinsulin;Proinsulin precursor;IDDM;IDDM1;IDDM2;ILPR;ins;INS;Insulin A chain;Insulin B chain;IRDN;MODY10;Preproinsulin;Proinsulin;Proinsulin precursor;Pro-Insulin
Application:
IHC-Paraffin
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
A1162
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant Human Insulin Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody