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Antibodies

Recombinant Phospho-IGF1R (Tyr1131)/Insulin Receptor B Beta (Tyr1146) Monoclonal Antibody

Product Sizes
20 ul
£189.00
AN300051L-20UL
100 ul
£402.00
AN300051L-100UL
About this Product
SKU:
AN300051L
Additional Names:
JTK;IGF1R;CD221;IGFIR;IGFR;JTK13;CD221 antigen;IGF-1R;IGF-I R;IGF-I receptor;IGF-IR;insulin-like growth factor 1 receptor
Application:
Western Blot
Buffer:
10 mM sodium HEPES, 150 mM NaCl, 100 ug/mL protein protectant, 50% glycerol, pH 7.5
translate.label.attr.clone:
A1161
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
A synthetic phosphopeptide corresponding to residues around Tyr1131 of the Human Phospho-IGF1R or Tyr1146 of the Human Insulin Receptor B Beta
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody