CTLA-4 Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN200208P-100UL
About this Product
- SKU:
- AN200208P
- Additional Names:
- GRD;ALPS;IDDM;Cytotoxic T-lymphocyte protein;Cytotoxic T-lymphocyte-associated antigen;Cytotoxic T-Lymphocyte-Associated Protein;CELIAC;CTLA4;ALPS5;CD;CD152;CELIAC3;CTLA-4;GRD4;GSE;IDDM12;Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;Cytotoxic T-Lymphocyte-Associated Protein 4
- Application:
- Western Blot
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- A1060
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
- Host:
- Mouse
- Immunogen:
- Recombinant Human CTLA-4 Protein
- Isotype:
- IgG1
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-ctla_4_monoclonal_antibody-an200208p
