IL-32 alpha/IL32A Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN200201P-100UL
About this Product
- SKU:
- AN200201P
- Additional Names:
- TAIFa,IL-32alpha,IL-32beta,IL-32delta,IL-32gamma,TAIFb,TAIFc,TAIFd,IL32,NK4,TAIF,IL 32alpha,IL 32beta,IL 32delta,IL 32gamma,IL-32,Interleukin 32,Interleukin 32 small,Interleukin 32 theta,Interleukin-32,interleukin-32 eta,Natural killer cell transcript 4,Natural killer cells protein 4,NK 4,OTTHUMP00000236040,OTTHUMP00000236041,OTTHUMP00000236042,OTTHUMP00000236043,OTTHUMP00000236044,OTTHUMP00000236045,OTTHUMP00000236046,OTTHUMP00000236047,OTTHUMP00000236048,OTTHUMP00000236049,OTTHUMP00000236050,OTTHUMP00000236051,OTTHUMP00000236052,OTTHUMP00000236053,OTTHUMP00000236054,OTTHUMP00000241545,OTTHUMP00000241602,OTTHUMP00000241603,OTTHUMP00000241604,OTTHUMP00000241605,OTTHUMP00000241606,OTTHUMP00000241607,OTTHUMP00000241608,OTTHUMP00000241609,OTTHUMP00000241610,OTTHUMP00000241611,OTTHUMP00000241612,Tumor necrosis factor alpha-inducing factor
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- A1053
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.
- Host:
- Mouse
- Immunogen:
- Recombinant Human IL-32 alpha/IL32A Protein
- Isotype:
- IgG2a
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:il32a_monoclonal_antibody-an200201p
