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Antibodies

P4HB/ERBA2L Monoclonal Antibody

Product Sizes
20 ul
£167.00
AN200187P-20UL
100 ul
£346.00
AN200187P-100UL
About this Product
SKU:
AN200187P
Additional Names:
PDIA,CLCRP,P4HB,CLCRP1,DSI,ERBA2L,GIT,P4Hbeta,PDI,PDIA1,PHDB,PO4DB,PO4HB,PROHB,Cellular thyroid hormone-binding protein,p55,Prolyl 4-hydroxylase subunit beta,Protein Disulfide-Isomerase
Application:
IHC-Paraffin
Buffer:
PBS
translate.label.attr.clone:
A1039
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
Host:
Mouse
Immunogen:
Recombinant Human P4HB protein
Isotype:
IgG1
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody