RPRD1B Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN200140P-100UL
About this Product
- SKU:
- AN200140P
- Additional Names:
- NET,C20orf,dJ1057B,RPRD1B,C20orf77,CREPT,NET60,dJ1057B20.2,K-H,Kub5-Hera
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- A988
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN2B or cyclin-A. Promotes cell proliferation.
- Host:
- Mouse
- Immunogen:
- Recombinant Human RPRD1B Protein
- Isotype:
- IgG2b
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-rprd1b_monoclonal_antibody-an200140p
