PRTFDC1 Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN200139P-100UL
About this Product
- SKU:
- AN200139P
- Additional Names:
- PRTFDC,HHGP,PRTFDC1
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- A987
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease(LND). LND is a severe X-linked neurological disorder caused by a deficiency of hypoxanthine phosphoribosyltransferase. PRTFDC1 has a low, barely measurable phosphoribosyltransferase activity (in vitro).
- Host:
- Mouse
- Immunogen:
- Recombinant Human PRTFDC1 protein
- Isotype:
- IgG1
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-prtfdc1_monoclonal_antibody-an200139p
