IL17RA/CD217 Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN200111P-100UL
About this Product
- SKU:
- AN200111P
- Additional Names:
- IMD,MGC,CTLA,CANDF,CDw,IL17RA,CANDF5,CD217,CDw217,IL-17RA,IL17R,IMD51,hIL-17R,CD127,CD217 antigen,CDW127,CTLA8,HIL 17R,hIL17R,I17RA,IL 17 receptor,IL 17 receptor A,IL 17RA,IL17,IL-17 R alpha,IL-17 receptor A,IL17A receptor,IL-17R,IL17R-A,IL17-RA,IL-17R-alpha,IL7RA,ILRA,Interleukin 17 receptor A,Interleukin-17 receptor A,MGC10262,CDw217,Interleukin-17 receptor A
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- A959
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor A (IL-17 RA), also known as IL-17 receptor (IL-17 R). IL-17 RA shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 RA mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. Human IL-17 RA is a 120 kDa, 866 amino acid (aa) type I membrane glycoprotein with a 293 aa extracellular domain, a 21 aa carboxy-proximal transmembrane domain, and a 525 aa cytoplasmic tail. Within the ECD, human IL-17 RA shares 72% aa sequence identity with mouse and rat IL-17 RA. The signaling events of IL-17 includes activation of NF-kappa B and JNK, and require TNF receptor-associated factors 6 (TRAF6) in the signaling pathway.
- Host:
- Mouse
- Immunogen:
- Recombinant Human IL17RA protein
- Isotype:
- IgG1
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:cd217_monoclonal_antibody-an200111p
