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Antibodies

RRM1 Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN200083P-100UL
About this Product
SKU:
AN200083P
Additional Names:
RIR,RRM,RRM1,R1,RIR1,RR1,large subunit,M1 subunit,Ribonucleoside diphosphate reductase large subunit,Ribonucleoside diphosphate reductase M1 chain,Ribonucleoside diphosphate reductase subunit M1,Ribonucleoside reductase,Ribonucleoside-diphosphate reductase large subunit,Ribonucleoside-diphosphate reductase subunit M1,Ribonucleotide reductase,Ribonucleotide reductase large chain,Ribonucleotide reductase large subunit,Ribonucleotide reductase M1,Ribonucleotide reductase M1 polypeptide,Ribonucleotide reductase R1 subunit,RIR 1,RR 1,RRM 1
Application:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Buffer:
PBS
translate.label.attr.clone:
A931
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.
Host:
Mouse
Immunogen:
Recombinant Human RRM1 protein
Isotype:
IgG1
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Flow cytometric analysis of Human RRM1 expression on HeLa cells. The cells were stained with purified anti-Human RRM1, then a PE-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Immunofluorescence analysis of Human RRM1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human RRM1 Monoclonal Antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 594-conjugated Goat Anti-mouse IgG secondary antibody (red) and counterstained with DAPI for nuclear staining (blue). Positive staining was localized to cytoplasm.