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Antibodies

Adenosine Deaminase Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN200057P-100UL
About this Product
SKU:
AN200057P
Additional Names:
ADA,adenosine deaminase,adenine deaminase,Adenosine Aminhydrolase,EC 3.5.4.4,ADA1,Adenosine aminohydrolase
Application:
Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
A905
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Adenosine Deaminase (ADA, adenosine aminohydrolase) is one of the key enzymes of purine nucleotide catabolism. It catalyses the hydrolytic deamination of adenosine and deoxy-adenosine to inosine and deoxyinosine . ADA is expressed in virtually all tissues and is expressed at high levels in T-lymphocytes. Adenosine Deaminase deficiency can cause a form of SCID (severe combined immunodeficiency) and lymphopenia in both B- and T-cell lineages . ADA can be used as a sensitive diagnostic marker for tuberculous pleuritis . Although it is primarily a cytosolic enzyme, ADA is known to be a positive regulator of T-cell co-activation due to its binding to CD26 at the cell surface. The interaction of ADA with CD26 regulates lymphocyte-epithelial cell adhesion
Host:
Mouse
Immunogen:
Recombinant Human Adenosine Deaminase Protein
Isotype:
IgG1
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody